Katherine Cassavetes (1906-1983) was an American actress, primarily known for her contribution to the independent cinema of her son, the celebrated director John Cassavetes.

Her film career was inextricably linked to Cassavetes' works, where she played supporting roles, often portraying maternal or elderly female figures of Greek descent, imbuing her performances with a unique depth and authenticity. Among her most significant films are "Minnie and Moskowitz" (1971), "Una moglie" (A Woman Under the Influence, 1974), where she delivered a memorable performance as Gena Rowlands' mother, "Opening Night" (1977), and "Love Streams" (1984).

Her acting style was characterized by a straightforward realism and naturalness that perfectly blended with Cassavetes' semi-improvised and intimate filmmaking approach, making her a familiar and beloved face for fans of his work.